Adamawa Plateau, the northern part of the Cameroon Volcanic Line (CVL) is known to be the only habitat of one of Cameroon's most endangered frogs, Astylosternus nganhanus Amiet 1977. However, despite having sites of global conservation importance and key sites for woodland savannah batracofaunal diversity, this part of CVL has received very little biological exploration and conservation attention. Since the first description of A. nganhanus (1977), no detailed studies have been carried out in the region to assess the status of the amphibians and document further details on the species. In addition, we found that most of the species in the CVL were threatened with extinction due to anthropogenic activities leading to the degradation and disappearance of natural habitats, mainly montane forests. We also confirmed the presence of the pathogen Batrachochytrium dendrobatidis on Mount Manengouba. This pathogen causes a fungal disease (chytridiomycosis) that is considered to be a major factor in the decline of amphibian populations in mountainous regions. These different threat factors identified in the southern part of CVL may be more sensitive to mountain’s gallery forest species in the northern part due to the aridification of northern Cameroon and the scarcity of amphibian habitats.