As durian demand from China rises, tropical rainforests have been cleared to establish more monoculture durian plantations. As of 2021, China has imported at least 820,000 tons of durian from Southeast Asia as a result from Regional Comprehensive Economic Partnership (RCEP), and Belt and Road Initiative (BRI) between the countries. From small traditional orchards planted by locals where fruiting trees were intercropped, durian plantation has grown larger to industrial scale in which monoculture management is favoured more. Over the years, durian monoculture management has become number one contributor towards deforestation in Peninsular Malaysia and Southeast Asia. While land clearing has already destroyed habitats for wildlife, pesticide applications have also affected wildlife species richness and abundance especially in monoculture durian farming. Hence, mixed-plantations and wildlife-friendly farming should be seriously considered by durian stakeholders and farmers. Existing durian plantations, particularly traditional managed ones can still support some bird and frog species with polyculture system and maintaining forest patches within and surrounding plantations. More attention should be given to intercropping system by cultivating other native fruit trees (e.g mangosteen, jackfruit) in durian orchards to introduce more complex vegetation structure and increase resources for wildlife.